A STUDY TO EVALUATE AND COMPARE THE EFFICACY AND SAFETY OF TOPICAL CYCLOSPORINE-A 0.5% WITH TOPICAL PLACEBO (ARTIFICIAL TEARS) IN ALLEVIATING THE CLINICAL FEATURES ASSOCIATED WITH VERNAL KERATOCONJUNCTIVITIS

A STUDY TO EVALUATE AND COMPARE THE EFFICACY AND SAFETY OF TOPICAL CYCLOSPORINE-A 0.5% WITH TOPICAL PLACEBO (ARTIFICIAL TEARS) IN ALLEVIATING THE CLINICAL FEATURES ASSOCIATED WITH VERNAL KERATOCONJUNCTIVITIS

Introduction: Vernal keratoconjunctivitis is a severe, typically seasonal recurrent ocular inflammatory disorder.Topical cyclosporine-A is inhibitory to many T-cell dependent inflammatory mechanisms which are likely to play role in Jacket treatment of vernal keratoconjunctivitis.Methodology: The study was conducted on 100 patients of vernal keratoc

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Vitamin D3 induces mesenchymal-to-endothelial transition and promotes a proangiogenic niche through IGF-1 signaling

Summary: Although vitamin D3 (VitD3) prevents angiogenesis in cancer, VitD3 deficiency is associated with greater incidence of cardiovascular events in patients.We examined the influence of VitD3 on the angiogenic potential of mesenchymal stem Baby Pants cells (MSCs).VitD3 treatment increased the expression of proangiogenic molecules in MSCs, which

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